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Tigers vs. Guardians Odds & Betting Predictions - September 24, 2025

Tigers at Guardians

10:40 pm • FDSDET

Detroit Tigers

10-10
1
1 - 5

Cleveland Guardians

11-10
5
Starting Pitchers
pitcherteameraw-l
Tanner Bibee logoT.BibeeCleveland Guardians logo4.2512-11
Jack Flaherty logoJ.FlahertyDetroit Tigers logo4.648-15

Tigers at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Tigers
10-10
-1.5
+1.5-186
o7.5-115
+119
Guardians
11-10
u8
-1.5+151
u7.5-105
-146
location pinWednesday 10:40 p.m.
September 24, 2025
Progressive FieldCleveland
Tigers vs. Guardians Expert Picks
New Owner
New Owner
Last 30d: 95-100-0 (+21.0u)
DET +118 (Live)
1u
The Degenerates
The Degenerates
Last 30d: 92-83-5 (+4.0u)
CLE -142
1u
Wags Wins
Wags Wins
Last 30d: 214-236-1 (-10.5u)
Under 8-119
1.26u
YBK Picks.com
Last 30d: 51-46-3 (-7.2u)
CLE -1+100
2u
Picks Office
Picks Office
Last 30d: 203-199-6 (-9.9u)
CLE -120
0.83u
Grant Neiffer
Grant Neiffer
Last 30d: 20-104-3 (+2.7u)
J.Ramirez o0.5 HR+450
0.25u
R.Greene o0.5 HR+425
0.25u
Bet Labs
Bet Labs
Last 30d: 12-13-0 (-2.6u)
CLE -153
0.93u
Lines at Lunch
Lines at Lunch
Last 30d: 0-0-0 (+0.0u)
Over 7.5-115
1.15u
Sean Zerillo
Sean Zerillo
Last 30d: 162-160-9 (-8.6u)
Over 7.5-108
0.54u
Bet to -115

Tigers vs. Guardians Previews & Analysis

  • 3 MLB Player Props for Wednesday, 9/24 article feature image

    3 MLB Player Props for Wednesday, 9/24

    Alex Hinton•
    Sep 24, 2025 UTC
  • Tigers vs Guardians: Back the Red-Hot Guardians article feature image

    Tigers vs Guardians: Back the Red-Hot Guardians

    Action Network Staff•
    Sep 24, 2025 UTC
  • Zerillo's Opening Pitch for Wednesday article feature image

    Zerillo's Opening Pitch for Wednesday

    Sean Zerillo•
    Sep 24, 2025 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Tigers vs. Guardians Public Betting Percentages

Away Logo

Tigers

Public

Home Logo

Guardians

30%

Bets%

70%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Guardians are 2-3 in their last 5 games.
  • Guardians are 2-3 in their last 5 games against the spread
  • Guardians are 6-7 in their road games against the spread
  • The totals have gone OVER in 3 of Guardians' last 5 games
  • The totals have gone OVER in 3 of Guardians' 8 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians		12-96-26-74-38-6
Tigers		10-107-23-87-63-3

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians		10-113-57-63-47-7
Tigers		8-10-23-4-25-64-7-23-3

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians		11-105-36-74-37-7
Tigers		10-108-12-98-52-4

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 23rdDETW 5-2+1.5 WO 6.5CLE +136
Sep 21st@MINL 2-6-1.5 LU 8.5MIN -143
Sep 20th@MINW 8-0-1.5 WU 8.5CLE -108
Sep 20th@MINW 6-0---
Sep 20th@MINW 6-2-1.5 WO 7.5CLE -113

Guardians vs. Tigers Injury Updates

Guardians Injuries

    Tigers Injuries

    • Reese Olson
      SP

      Olson is out with shoulder

      Out

    • Jackson Jobe
      SP

      Jobe is out with elbow

      Out

    • Trey Sweeney
      SS

      Sweeney is out with shoulder

      Out

    • Sawyer Gipson-Long
      SP

      Gipson-Long is out with oblique

      Out

    • Beau Brieske
      RP

      Brieske is out with groin

      Out

    • Troy Melton
      SP

      Melton is out with elbow

      Out

    See more MLB Injuries Right Arrow
    Tigers vs. Guardians Box Score
    Tigers Player Stats
    Projected
    PITCHERPCIPKER
    Jack Flaherty logoRJ.Flaherty, P834.163
    Tyler Holton logoLT.Holton, P211.220
    Rafael Montero logoRR.Montero, P14000
    Will Vest logoRW.Vest, P19110
    Paul Sewald logoRP.Sewald, P8100
    HITTERSH-ABRHRRBI
    Parker Meadows logo1P.Meadows, CF0-2001
    Jahmai Jones logo1J.Jones, PH0-1000
    Jahmai Jones logo1J.Jones, RF0-1000
    Gleyber Torres logo2G.Torres, 2B1-4000
    Kerry Carpenter logo3K.Carpenter, DH0-4000
    Spencer Torkelson logo4S.Torkelson, 1B1-4000
    Riley Greene logo5R.Greene, LF1-3000
    Wenceel Perez logo6W.Perez, RF0-3000
    Wenceel Perez logo6W.Perez, CF0-3000
    Zach McKinstry logo7Z.McKinstry, 3B1-3000
    Zach McKinstry logo7Z.McKinstry, SS1-3000
    Dillon Dingler logo8D.Dingler, C1-4100
    Trey Sweeney logo9T.Sweeney, SS1-2000
    Andy Ibanez logo9A.Ibanez, PH0-1000
    Andy Ibanez logo9A.Ibanez, 3B0-1000
    Guardians Player Stats
    Projected
    PITCHERPCIPKER
    Tanner Bibee logoRT.Bibee, P105651
    Tim Herrin logoLT.Herrin, P140.210
    Hunter Gaddis logoRH.Gaddis, P60.110
    Jakob Junis logoRJ.Junis, P281.220
    Cade Smith logoRC.Smith, P20.100
    HITTERSH-ABRHRRBI
    Steven Kwan logo1S.Kwan, LF1-4001
    George Valera logo2G.Valera, DH1-4112
    Jose Ramirez logo3J.Ramirez, 3B2-4002
    Kyle Manzardo logo4K.Manzardo, 1B0-4000
    Jhonkensy Noel logo4J.Noel, 1B0-0000
    Bo Naylor logo5B.Naylor, C1-4000
    Gabriel Arias logo6G.Arias, SS0-4000
    Daniel Schneemann logo7D.Schneemann, CF0-3100
    Daniel Schneemann logo7D.Schneemann, RF0-3100
    CJ Kayfus logo8C.Kayfus, RF1-3000
    Petey Halpin logo8P.Halpin, PR0-1100
    Petey Halpin logo8P.Halpin, CF0-1100
    Brayan Rocchio logo9B.Rocchio, 2B2-2200

    Tigers vs. Guardians Odds Comparison

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    Tigers at Guardians Team Totals

    MatchupOverUnder
    Tigers
    10-10
    N/A
    N/A
    Guardians
    11-10
    N/A
    N/A