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Pacers vs. Cavaliers Odds & Betting Predictions - November 22, 2025

Pacers at Cavaliers

12:00 am • Amazon Prime Video

Indiana Pacers

19-63
109
109 - 120

Cleveland Cavaliers

1-0
120

Pacers at Cavaliers Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Pacers
19-63
N/A
N/A
N/A
Cavaliers
1-0
N/A
N/A
N/A
location pinSaturday 12:00 a.m.
November 22, 2025
Rocket ArenaCleveland
Pacers vs. Cavaliers Expert Picks
YBK Picks.com
Last 30d: 40-41-3 (-17.4u)
Over 241.5-105
2u
Cam Is Money
Cam Is Money
Last 30d: 104-77-3 (+24.9u)
B.Mathurin o20.5 Pts-112
0.89u
Matt DiLeo
Matt DiLeo
Last 30d: 46-38-1 (+3.3u)
J.Tyson o12.5 Pts+Rebs-115
0.87u
Matt Moore
Matt Moore
Last 30d: 23-38-0 (+3.1u)
Under 241.5-110
0.1u
Kyle Murray
Kyle Murray
Last 30d: 64-129-5 (-27.2u)
B.Mathurin o20.5 Pts-115
1u
The Degenerates
The Degenerates
Last 30d: 86-80-5 (+1.2u)
P.Siakam o23.5 Pts-114
1u
Ryan Minion
Ryan Minion
Last 30d: 222-284-4 (-5.1u)
B.Mathurin o21.5 Pts-105
$1.05
B.Mathurin o29.5 Pts+Rebs+Ast-105
$1.00
Buckets Podcast
Buckets Podcast
Last 30d: 76-72-1 (+0.6u)
D.Mitchell u37.5 Pts+Rebs+Ast-114
0.5u
@ChicagoFlow ⭐️⭐️ https://myaction.app/v5zzJuSFtYb
RoyalsProps
RoyalsProps
Last 30d: 62-54-6 (+2.9u)
CLE o126.5-120
1.2u

Pacers vs. Cavaliers Previews & Analysis

  • NBA Player Props: 3 Picks for Friday article feature image

    NBA Player Props: 3 Picks for Friday

    Action Network Staff•
    Nov 21, 2025 UTC
  • Pacers vs Cavaliers: Moore's Over/Under Pick for Friday article feature image

    Pacers vs Cavaliers: Moore's Over/Under Pick for Friday

    Matt Moore•
    Nov 21, 2025 UTC
  • NBA Cup Best Bets: 6 Picks for Thursday article feature image

    NBA Cup Best Bets: 6 Picks for Thursday

    Action Network Staff•
    Nov 21, 2025 UTC
See more NBA Coverage Right Arrow

Prop Odds Comparison

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Line Movement Tracker

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Pacers vs. Cavaliers Public Betting Percentages

Away Logo

Pacers

Public

Home Logo

Cavaliers

50%

Bets%

50%

Money%

NBA Public Betting Right Arrow

Betting Trends

  • Cavaliers are 4-1 in their last 5 games.
  • Cavaliers are 3-2 in their last 5 games against the spread
  • Cavaliers are 17-24 in their road games against the spread
  • The totals have gone OVER in 3 of Cavaliers' last 5 games
  • The totals have gone OVER in 17 of Cavaliers' 41 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Cavaliers		33-4916-2517-2424-429-7
Pacers		40-4224-1716-254-636-35

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Cavaliers		40-41-117-2423-17-133-32-17-9
Pacers		41-4121-2020-212-839-32

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Cavaliers		52-30N/AN/A45-217-9
Pacers		19-63N/AN/A4-615-56

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Nov 20thHOUL 104-114+1.5 LU 233.5HOU +103
Nov 18thMILW 118-106-5.5 WU 234.5CLE -260
Nov 15thMEMW 108-100---
Nov 14thTORL 113-126-7.5 LO 238.5TOR -285
Nov 13th@MIAW 130-116+4.5 WO 239.5CLE +160

Cavaliers vs. Pacers Injury Updates

Cavaliers Injuries

  • Thomas Bryant
    C

    Thomas Bryant (calf) out Monday.

    Out

  • Jaylon Tyson
    PF

    Jaylon Tyson (toe) probable Friday.

    Probable

Pacers Injuries

  • T.J. McConnell
    PG

    T.J. McConnell (injury management) out Friday.

    Out

  • Ivica Zubac
    C

    Zubac is out with ribs

    Out

  • Pascal Siakam
    PF

    Siakam is out with ankle

    Out

  • Tyrese Haliburton
    PG

    Haliburton is out with achilles

    Out

  • Aaron Nesmith
    SF

    Aaron Nesmith (neck) out Friday.

    Out

  • Obi Toppin
    PF

    Obi Toppin (back) probable Sunday.

    Probable

  • Andrew Nembhard
    SG

    Andrew Nembhard (injury management) out Friday.

    Out

  • Ben Sheppard
    SG

    Ben Sheppard (hip) out Sunday.

    Out

  • Jarace Walker
    PF

    Jarace Walker (foot) out Sunday.

    Out

  • Johnny Furphy
    SG

    Furphy is out with knee

    Out

See more NBA Injuries Right Arrow
Player Stats
  • scoring
    Donovan Mitchell logo
    Donovan Mitchell
    32
    ppg
  • rebounding
    Evan Mobley logo
    Evan Mobley
    12
    rpg
  • assists
    player logo
    -
    7
    apg
  • shooting
    Jaylon Tyson logo
    Jaylon Tyson
    85.7
    fg%
Team Stats

37-88 (42%)
Field Goals
43-89 (48%)
24-26 (92%)
Free Throws
21-27 (78%)
11-37 (30%)
3P
13-35 (37%)
43
Rebounds
52
25
Assists
28
Turnovers
10
Steals
5
5
Blocks
8
22
Fouls
22

Pacers vs. Cavaliers Odds Comparison

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Pacers at Cavaliers Team Totals

MatchupOverUnder
Pacers
19-63
N/A
N/A
Cavaliers
1-0
N/A
N/A