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Cardinals vs. Astros Odds & Betting Predictions - April 18, 2026

Cardinals at Astros

11:10 pm • CARD

St. Louis Cardinals

11-8
@

Houston Astros

8-13
Starting Pitchers
pitcherteameraw-l
Lance McCullers logoL.McCullersHouston Astros logo5.871-0
Andre Pallante logoA.PallanteSt. Louis Cardinals logo4.801-1

Cardinals at Astros Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Cardinals
11-8
+1.5
+1.5-173
o9-105
+119
Astros
8-13
u8.5
-1.5+144
u9-115
-145
location pinSaturday 11:10 p.m.
April 18, 2026
Daikin ParkHouston
thermometer image75°Fahrenheit
rain image46%Rain
wind image9Wind
Cardinals vs. Astros Expert Picks
Ryan Minion
Ryan Minion
Last 30d: 219-278-4 (-19.2u)
J.Walker o1.5 Hits + Runs + RBIs-117
$1.17
RoyalsProps
RoyalsProps
Last 30d: 62-53-5 (+3.7u)
J.Walker o1.5 Hits + Runs + RBIs-112
1.12u
C.Smith o1.5 Hits + Runs + RBIs-110
1.1u
Matt Trollo
Matt Trollo
Last 30d: 34-47-6 (-9.4u)
HOU o4.5-104
1.04u
(FD) Saturday's Opening Pitch (Play to -140, decrease size above -120)

Cardinals vs. Astros Previews & Analysis

  • Cardinals vs Astros: Great Matchup for Houston article feature image

    Cardinals vs Astros: Great Matchup for Houston

    Matt Trollo•
    Apr 18, 2026 UTC
  • Trigger's Triple-A Picks For Saturday article feature image

    Trigger's Triple-A Picks For Saturday

    Adam Trigger•
    Apr 18, 2026 UTC
  • Saturday's Opening Pitch featuring Matt Trollo article feature image

    Saturday's Opening Pitch featuring Matt Trollo

    Matt Trollo•
    Apr 18, 2026 UTC
  • MLB Picks, Predictions Today: 4 Best Bets for Royals vs. Yankees, Tigers vs. Red Sox, More for April 18 article feature image

    MLB Picks, Predictions Today: 4 Best Bets for Royals vs. Yankees, Tigers vs. Red Sox, More for April 18

    Action Network Staff•
    Apr 18, 2026 UTC
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Prop Odds Comparison

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Line Movement Tracker

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Cardinals vs. Astros Public Betting Percentages

Away Logo

Cardinals

Public

Home Logo

Astros

46%

Bets%

54%

Money%

MLB Public Betting Right Arrow

Betting Trends

  • Astros are 2-3 in their last 5 games.
  • Astros are 1-4 in their last 5 games against the spread
  • Astros are 2-8 in their road games against the spread
  • The totals have gone OVER in 2 of Astros' last 5 games
  • The totals have gone OVER in 7 of Astros' 11 last games at home

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Astros		8-136-52-84-94-3
Cardinals		11-87-54-31-110-7

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Astros		13-7-17-46-3-17-65-1-1
Cardinals		11-7-17-54-2-11-110-6-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Astros		8-137-41-95-83-4
Cardinals		11-87-54-31-110-7

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Apr 18thSTLL 4-9-O 9STL -125
Apr 17thCOLL 2-3-1.5 LU 8.5COL -171
Apr 16thCOLW 3-1-1.5 WU 8.5HOU -196
Apr 15thCOLW 7-6-1.5 LO 8.5HOU -186
Apr 13th@SEAL 2-6+1.5 LU 8SEA +149

Astros vs. Cardinals Injury Updates

Astros Injuries

  • Zach Dezenzo
    LF

    Dezenzo is out with elbow

    Out

Cardinals Injuries

  • Jose Fermin
    2B

    Jose Fermin has been scratched Tuesday.

    Out

  • Lars Nootbaar
    LF

    Nootbaar is out with heel

    Out

  • Hunter Dobbins
    SP

    Dobbins is out with knee

    Out

See more MLB Injuries Right Arrow
Cardinals vs. Astros Starting Lineups
Cardinals Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Andre Pallante logoRA.Pallante, P1-14.801.5334.20
HITTERSAVGOBPSLGHR
JJ Wetherholt logo1J.Wetherholt, 2B.232.368.3773
Ivan Herrera logo2I.Herrera, DH.212.398.3482
Alec Burleson logo3A.Burleson, 1B.292.388.4312
Jordan Walker logo4J.Walker, RF.315.375.6858
Nolan Gorman logo5N.Gorman, 3B.207.284.3623
Masyn Winn logo6M.Winn, SS.189.328.2450
Nathan Church logo7N.Church, LF.214.261.3101
Pedro Pages logo8P.Pages, C.211.262.3421
Victor Scott logo9V.Scott, CF.235.273.2550
Astros Starting Lineup
Projected
PITCHERW-LERAWHIPK/9
Lance McCullers logoRL.McCullers, P1-05.871.3049.98
HITTERSAVGOBPSLGHR
Jose Altuve logo1J.Altuve, 2B.293.404.4933
Yordan Alvarez logo2Y.Alvarez, DH.333.479.7508
Isaac Paredes logo3I.Paredes, 3B.200.333.2730
Christian Walker logo4C.Walker, 1B.278.369.5284
Carlos Correa logo5C.Correa, SS.271.346.3861
Joey Loperfido logo6J.Loperfido, LF.259.333.3450
Cam Smith logo7C.Smith, RF.264.349.4583
Taylor Trammell logo8T.Trammell, CF.300.391.3500
Yainer Diaz logo9Y.Diaz, C.186.222.2541

Cardinals vs. Astros Odds Comparison

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Cardinals at Astros Team Totals

MatchupOverUnder
Cardinals
11-8
N/A
N/A
Astros
8-13
N/A
N/A